17-OH Progesterone

Sample: Serum 1.0 mL

Schedule: Friday (RIA Test)

Units: ng/mL 

Range: 0.2 - 2.6   Follicular
            0.3 - 4.0   Luteal
            1.0 - 1.7   Contraceptive
            0.1 - 1.2   Postmeno
           < 1.8        Prepubertal

           0.4 - 3.5   Males 



17a-Hydroxy Progesterone is produced in the adrenals, testes, ovaries and placenta and is an intermediate product in the synthesis of Cortisol. High levels of 17-OHa-Progesterone are seen in patients with congenital adrenal hyperplasia (adrenogenital syndrome). 

Deficiency of the enzyme 21-Hydroxylase blocks the normal synthesis of cortisol leading to compensatory increase of ACTH secretion. This results in adrenal hyperplasi with increased levels of 17a-Hydroxy Progesterone, DHEA and other adrenal steroids. 17a-Hydroxy Progesterone is useful in evaluation of hirsutism and/or infertility and to assess certain adrenal or ovarian tumors with endocrine activity.


Available tests