Sample: Whole blood (EDTA, Heparin, Citrate, etc.) 0.5 mL
Units: % of total Hb
Range: 4 - 6 % Non diabetics < 7% Well control 7 - 10% Average control > 10% Poor contro.
Remarks: Glycosylated hemaoglobin (HbA1c ) is used to assess blood glucose control in diabetic patients whose serum glucose levels are labile and single blood glucose measurements may not accurately reflect the true glucose level over few weeks. HbA1c value reflects the average blood glucose level for the last 3 - 4 weeks (this is the average half-life of RBCs in blood, where the HbA1c is stored). Similarly to HbA1c, serum Fructosamine (glycated serum protein) may be used to assess the blood glucose control, for a short interval of 2 - 3 weeks ( the average half-life of albumin in plasma, where the fructosamine is stored).