Depakene (Valproic Acid)
Sample: Serum
Schedule: Daily
Units: μmol/L
Range: Therapeutic range : 346 - 700 (Convertion: μmol/L x 0,1442 = μg/mL)
Remarks: Valproic acid (Depakene) is a first-choice drug for absence of seizures, generalized seizures and for the epileptic syndromes. (Synonyms: Depakene®, Depamide®, Divalproex®, Epilim®, Valproate®).
| Drug | Therapeutic Range | Toxic Level | Half-Live |
| Carbamazepine (Tegretol) | 8 - 12 μg/mL | > 12 μg/mL | 15 - 40 hrs |
| Digitoxin | 18 - 35 ng/mL | > 35 ng/mL | 150 - 250 hrs |
| Digoxin | 0.8 - 2.0 ng/mL | > 2.0 ng/mL | 20 - 60 hrs |
| Phenobarbital | 20 - 40 μg/mL | > 40 μg/mL | 50 - 140 hrs |
| Phenytoin (Epanutin) | 10 - 20 μg/mL | > 20 μg/mL | 20 - 40 hrs |
| Valproic Acid (Depakene) | 346 - 700 μmol/L | >700 μmol/L | 8 - 15 hrs |
