Anti HBs (Quantitative)
Sample: Serum
Schedule: Daily
Units: mIU/mL
Range: > 10 mIU/mL : Immunity
Remarks: The appearance of anti-HBs (antibodies to the surface antigen of hepatitis B virus)usually follows the disappearance of the same surface antigen of the hepatitis B (HBsAg). Anti HBs persist for years and is associated with immunity to hepatitis B. Response to Hepatitis B vaccine depends strongly on age, sex, obesity, and general health. About 95% of healthy, thin women in their 20s will develop antibodies after a three-dose course. Twenty-five to 50 percent of non-responders will ultimately seroconvert after a repeat course. Assessing responsiveness in vaccinees is only recommended in high risk patients. Levels less than 10 mIU/mL are considered negative and non-protective.
